Symptoms, complications and management of long COVID: a review

Author:

Aiyegbusi Olalekan Lee12345ORCID,Hughes Sarah E123ORCID,Turner Grace12,Rivera Samantha Cruz124,McMullan Christel12,Chandan Joht Singh1,Haroon Shamil1,Price Gary2,Davies Elin Haf6,Nirantharakumar Krishnarajah17,Sapey Elizabeth89,Calvert Melanie J12345ORCID,

Affiliation:

1. Institute of Applied Health Research, University of Birmingham, Birmingham, UK

2. Centre for Patient Reported Outcomes Research, Institute of Applied Health Research, University of Birmingham, Birmingham, UK

3. National Institute for Health Research (NIHR) Applied Research Centre West Midlands, Birmingham, UK

4. Birmingham Health Partners Centre for Regulatory Science and Innovation, University of Birmingham, Birmingham, UK

5. NIHR Birmingham Biomedical Research Centre, NIHR Surgical Reconstruction and Microbiology Research Centre, University of Birmingham, Birmingham, UK

6. Aparito Limited, Wrexham, UK

7. Midlands Health Data Research UK, Birmingham, UK

8. Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK

9. Acute Medicine, University Hospitals Birmingham NHS Foundation Trust, Edgbaston, Birmingham, UK

Abstract

Globally, there are now over 160 million confirmed cases of COVID-19 and more than 3 million deaths. While the majority of infected individuals recover, a significant proportion continue to experience symptoms and complications after their acute illness. Patients with ‘long COVID’ experience a wide range of physical and mental/psychological symptoms. Pooled prevalence data showed the 10 most prevalent reported symptoms were fatigue, shortness of breath, muscle pain, joint pain, headache, cough, chest pain, altered smell, altered taste and diarrhoea. Other common symptoms were cognitive impairment, memory loss, anxiety and sleep disorders. Beyond symptoms and complications, people with long COVID often reported impaired quality of life, mental health and employment issues. These individuals may require multidisciplinary care involving the long-term monitoring of symptoms, to identify potential complications, physical rehabilitation, mental health and social services support. Resilient healthcare systems are needed to ensure efficient and effective responses to future health challenges.

Funder

NIHR

Publisher

SAGE Publications

Subject

General Medicine

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