Blood Cholesterol and Coronary Heart Disease: Changing Perspectives-Reference-Cited by-同舟云学术

Blood Cholesterol and Coronary Heart Disease: Changing Perspectives

Published:1994-08 Issue:8 Volume:87 Page:450-453
ISSN:0141-0768
Container-title:Journal of the Royal Society of Medicine
language:en
Short-container-title:J R Soc Med

Author:

Temple Norman J¹,Walker Alexander R P²

Affiliation:

1. Faculty of Science, Athabasca University, Box 10,000, Athabasca, Alberta T0G 2R0, Canada

2. Human Biochemistry Research Unit, Department of Tropical Diseases, School of Pathology of the University of Witwatersrand, and the South African Institute for Medical Research, Johannesburg, South Africa 2000

Abstract

There has been much controversy concerning the value of efforts to reduce blood cholesterol levels. In this contribution, the risks and benefits of interventions are discussed. Lowering cholesterol level by drugs is not recommended except in a small minority of subjects at very high risk of coronary heart disease (CHD), since it causes an excess of non-CHD deaths. Dietary intervention, by contrast, is safe. However, for it to be effective it must be sufficiently vigorous to achieve a drop in blood cholesterol of at least 6%, though considerably more is preferable. This action should be part of a more general effort aimed at the prevention of all Western diseases based on changes in lifestyle.

Publisher

SAGE Publications

Subject

General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/014107689408700807

Reference46 articles.

1. Health policy on blood cholesterol. Time to change directions.

2. Report of the Conference on Low Blood Cholesterol: Mortality Associations.

3. The low cholesterol-mortality association in a national cohort