Transcutaneous Measurements of Oxygen Tension at Edges of Leg Ulcers: Preliminary Communication

Abstract

Using skin-surface sensors, transcutaneous oxygen tension (Tc Po2) has been measured at the edges of ulcers and at control sites proximal to wounds on the same legs. Tc Po2 at 43°C at the edges of venous ulcers was found to be significantly different ( P < 0.003) from that of arterial and mixed arteriovenous ulcers ( P < 0.05) respectively. Tc Po2 on healed skin was higher than at any wound edge. At this temperature Tc Po2 was also found to be significantly different ( P < 0.001) on the intact skin of patients with venous disease when compared with measurements at identical sites on healthy controls. In the same group, these Tc Po2 values increased with dependency. By contrast, at 37°C Tc Po2 was no different between groups ( P < 0.10), nor did it alter with position. This protocol adopted for investigating ulcers enables a quantitative distinction to be made between ulcers of different aetiologies. The differences in Tc Po2 between different ulcers and healed skin support the fibrin cuff mechanism which has been suggested as the cause of venous ulceration.