1. Newham University Hospital, Barts Health NHS Trust, London E13 8SL, UK
2. Centre for Medical Education, Institute of Health Sciences Education, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Whitechapel E1 2AD, UK
3. Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK
4. NIHR Barts Biomedical Research Centre, William Harvey Research Institute, Queen Mary University of London, London EC1A 7BE, UK