Methyldopa-Induced Syndrome of Inappropriate Antidiuretic Hormone Secretion and Bone Marrow Granulomatosis-Reference-Cited by-同舟云学术

Methyldopa-Induced Syndrome of Inappropriate Antidiuretic Hormone Secretion and Bone Marrow Granulomatosis

Published:1988-09 Issue:9 Volume:22 Page:700-701
ISSN:0012-6578
Container-title:Drug Intelligence & Clinical Pharmacy
language:en
Short-container-title:Drug Intelligence & Clinical Pharmacy

Author:

Varkel Yakov¹,Braester Andrei¹,Nusem David¹,Shkolnik Tamar²

Affiliation:

1. Department of Internal Medicine “A”

2. Research Laboratory, Western Galilee Regional Hospital, Nahariya, Israel

Abstract

A case of an elderly man who developed severe hyponatremia and bone marrow granulomatosis while taking methyldopa is described. The hyponatremia was found to be due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). Bone marrow biopsy revealed granulomas. A MEDLINE search of the English literature was done, yielding only one previous report of methyldopa-induced bone marrow granulomatosis and no previous reports of methyldopa-induced SIADH.

Publisher

SAGE Publications

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

Link

http://journals.sagepub.com/doi/pdf/10.1177/106002808802200911

Reference11 articles.

1. Adverse Reactions with Methyldopa-a Decade's Reports

2. The syndrome of inappropriate secretion of antidiuretic hormone

3. Drug-Induced Dilutional Hyponatremia

4. Hyponatremia due to antidepressant medications

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