Author:
Baldwin Charlene M.,Safferman Allan Z.
Abstract
We describe a patient who developed lithium toxicity when lisinopril was substituted for clonidine. Possible mechanisms of angiotensin-converting enzyme (ACE) inhibitor-induced lithium toxicity are discussed. Aggressive serum lithium concentration monitoring and a reduction in the dose of lithium is advised when using ACE inhibitors because of disturbances and shifts in fluid and electrolyte balance.
Subject
Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics
Cited by
24 articles.
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