Self-Initiated Modification of Hypertension Treatment in Response To Perceived Problems

Author:

Wallenius Sirpa H1,Vainio Kirsti K2,Korhonen Maarit Jh2,Hartzema Abraham G3,Enlund Hannes K2

Affiliation:

1. Department of Social Pharmacy, University of Kuopio, PO Box 1627, FIN-70211 Kuopio, Finland

2. Department of Social Pharmacy, University of Kuopio

3. Department of Pharmaceutical Policy and Evaluative Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC

Abstract

Objective: To assess the prevalence of patient-initiated modification of drug instructions and the association between different classes of problems and the modification of hypertension therapy. Design And Methods: In this cross-sectional study, all patients (n = 1215) who had been examined at a hypertension clinic during a 1-year period were surveyed. The response rate to the questionnaire was 85%. of the 1035 respondents, 623 currently taking antihypertensive medication (self-report) were included in the study. Results: Of the patients taking antihypertensive drugs, 36% admitted that they had tried to manage their condition with a lower dosage and/or fewer drugs than prescribed. The percentage of patients who modified their drug regimen decreased with increasing age. One or more problems with the treatment of hypertension were reported by 79% of the respondents. The odds ratio (95% confidence interval) for modification among patients who reported 1 or more problems compared with those not reporting any problem was 3.5 (2.12 to 5.67). The prevalence of modification increased with the number of problems; this was seen in all age groups and among men and women. Conclusions: Perceived problems in drug taking in the treatment of hypertension have an important impact on the prevalence of modifying drug instructions.

Publisher

SAGE Publications

Subject

Pharmacology (medical)

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