Fixed Drug Eruption of the Penis Due to Co-Trimoxazole-Reference-Cited by-同舟云学术

Fixed Drug Eruption of the Penis Due to Co-Trimoxazole

Published:1987-01 Issue:1 Volume:21 Page:41-42
ISSN:0012-6578
Container-title:Drug Intelligence & Clinical Pharmacy
language:en
Short-container-title:Drug Intelligence & Clinical Pharmacy

Author:

Amir Jacob,Shuper Avinoam,Varsano Izhak,Livni Ella,Mimouni Marc

Abstract

Fixed eruption of the penis, due to co-trimoxazole, is described in two boys. The eruption was accompanied by severe swelling of the penis, urine retention, and pain during micturition. The migration inhibiting factor assay for co-trimoxazole was negative, but the mast cell degranulation test was strongly positive, suggesting reaginic hypersensitivity reaction.

Publisher

SAGE Publications

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

Link

http://journals.sagepub.com/doi/pdf/10.1177/10600280870211P105

Reference5 articles.

1. Detection of Hypersensitivity by Indirect Rat Mast Cells Degranulation

2. Immunological mechanisms in the reaction between drugs and the skin

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