Cardiac Inflammatory Myofibroblastic Tumor

Author:

Eilers Amanda L.1,Nazarullah Alia N.2,Shipper Edward S.3,Jagirdar Jaishree S.2,Calhoon John H.1,Husain S. Adil1

Affiliation:

1. Department of Cardiothoracic Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA

2. Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA

3. Department of Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA

Abstract

Although inflammatory myofibroblastic tumors (IMTs) can be found in virtually every major organ, cardiac origin is rare. After recently providing care to a child who presented with a significant myocardial infarction, interest in this rare tumor was piqued. We describe a comprehensive review of cardiac IMT, including information on nomenclature, epidemiology, clinical features, pathogenesis, gross/histological features, immunohistochemical profile, diagnosis, treatment, and prognosis. Fifty-seven cases were identified in the literature. Interestingly, our case represents the seventh case of coronary artery involvement reported. Moreover, it was found that an initial presentation of sudden death most commonly involves the coronary arteries.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,General Medicine,Pediatrics, Perinatology and Child Health,Surgery

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