Acute Kidney Injury and Critical Cardiac Disease

Author:

Cooper David S.1,Charpie John R.2,Flores Francisco X.3,William Gaynor J.4,Salvin Joshua W.5,Devarajan Prasad6,Krawczeski Catherine D.7

Affiliation:

1. Divisions of Critical Care and Cardiology, The Congenital Heart Institute of Florida (CHIF), All Children’s Hospital, University of South Florida College of Medicine, Saint Petersburg, FL, USA

2. Division of Cardiology, C.S. Mott Children’s Hospital, University of Michigan School of Medicine, Ann Arbor, MI, USA

3. Division of Nephrology, All Children’s Hospital, University of South Florida College of Medicine, Saint Petersburg, FL, USA

4. Division of Cardiothoracic Surgery, The Cardiac Center, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA

5. Division of Cardiac Intensive Care, Department of Cardiology, Children’s Hospital Boston, Harvard University School of Medicine, Boston, MA, USA

6. Division of Nephrology and the Center for Acute Care Nephrology, Cincinnati Children’s Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA

7. The Heart Institute and the Center for Acute Care Nephrology, Cincinnati Children’s Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA

Abstract

The field of cardiac intensive care continues to advance in tandem with congenital heart surgery. The survival of patients with critical congenital heart disease is seldom in question. Consequently, the focus has now shifted to that of morbidity reduction and eventual elimination. Acute kidney injury (AKI) after cardiac surgery is associated with adverse outcomes, including prolonged intensive care and hospital stays, diminished quality of life, and increased long-term mortality. Acute kidney injury occurs frequently, complicating 30% to 40% of adult and pediatric cardiac surgeries. Patients who require dialysis are at high risk of mortality, but even minor degrees of postoperative AKI portend a significant increase in mortality and morbidity.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,General Medicine,Pediatrics, Perinatology, and Child Health,Surgery

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