Translational Research in Pediatric Extracorporeal Life Support Systems and Cardiopulmonary Bypass Procedures: 2011 Update

Author:

Qiu Feng1,Talor Jonathan1,Zahn Jeffrey2,Pauliks Linda1,Kunselman Allen R.1,Palanzo David1,Baer Larry1,Woitas Karl1,Wise Robert1,McCoach Robert1,Weaver Bonnie1,Carney Elizabeth1,Haines Nikkole1,Uluer Mehmet C.1,Aran Kiana2,Sasso Lawrance A.2,Alkan-Bozkaya Tijen3,Akcevin Atif3,Guan Yulong4,Wang Shigang4,Aĝirbaşli Mehmet5,Clark J. Brian1,Myers John L.1,Ündar Akif1

Affiliation:

1. Penn State Hershey Pediatric Cardiovascular Research Center, Departments of Pediatrics, Surgery, Bioengineering, Public Health Sciences, and Comparative Medicine, Penn State Hershey College of Medicine, Penn State Hershey Children’s Hospital, Hershey, PA, USA

2. Department of Bioengineering, Rutgers, The State University of New Jersey, Piscataway, NJ, USA

3. Department of Cardiovascular Surgery, American Hospital, Istanbul, Turkey

4. Department of Cardiopulmonary Bypass, The Fuwai Hospital, Beijing, China

5. Department of Cardiology, Marmara University, Istanbul, Turkey

Abstract

Over the past 6 years at Penn State Hershey, we have established the pediatric cardiovascular research center with a multidisciplinary research team with the goal to improve the outcomes for children undergoing cardiac surgery with cardiopulmonary bypass (CPB) and extracorporeal life support (ECLS). Due to the variety of commercially available pediatric CPB and ECLS devices, both in vitro and in vivo translational research have been conducted to achieve the optimal choice for our patients. By now, every component being used in our clinical settings in Penn State Hershey has been selected based on the results of our translational research. The objective of this review is to summarize our translational research in Penn State Hershey Pediatric Cardiovascular Research Center and to share the latest results with all the interested centers.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,General Medicine,Pediatrics, Perinatology, and Child Health,Surgery

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