Contributions of Proteome Profiling to the Molecular Analysis of Cancer

Author:

Wang Hong1,Hanash S. M.1

Affiliation:

1. University of Michigan Department of Pediatrics 1150 W. Medical Center Drive A520 MSRBI Ann Arbor, MI 48109, USA

Abstract

The proteome is the most functional compartment encoded for in the genome. Technologies for protein separation and quantitation, coupled with mass spectrometry for protein identification, have provided the means for proteome profiling of tumor cell lines and tissues that complement genomic and transcriptomic profiling. The application of established and novel proteomic technologies to the molecular analysis of cancer is reviewed.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology

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