Noninvasive Native Fluorescence Imaging of Head and Neck Tumors-Reference-Cited by-同舟云学术

Noninvasive Native Fluorescence Imaging of Head and Neck Tumors

Published:2002-02 Issue:1 Volume:1 Page:9-15
ISSN:1533-0346
Container-title:Technology in Cancer Research & Treatment
language:en
Short-container-title:Technol Cancer Res Treat

Author:

Katz A.¹,Savage Howard E.²,Schantz Stimson P.³,McCormick Steven A.²,Alfano R. R.¹

Affiliation:

1. New York State Center for Advanced Technology in Ultrafast Photonics Institute for Ultrafast Spectroscopy and Lasers Convent Avenue & 137 St. The City College of New York New York, NY 10031, USA

2. Department of Pathology New York Eye and Ear Infirmary 310 East 14th Street New York, NY 10003, USA

3. Department of Otolaryngology New York Eye and Ear Infirmary 310 East 14th Street New York, NY 10003, USA

Abstract

Fluorescence images were acquired from ex vivo head and neck tumor specimens. The excitation and emission wavelength combinations were selected to image emission from native tissue fluorophores (collagen, tryptophan, elastin and nicotinamide adenine dinucleotide). Two dimensional intensity ratio maps were generated from the fluorescence images and compared to histology images. The ratio maps accurately distinguished the regions of tumor from normal tissue in the specimens. Additional features, such as collagen capsules, blood vessels, mucus glands and muscles were evident in the fluorescence images.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology

Link

http://journals.sagepub.com/doi/pdf/10.1177/153303460200100102

Reference13 articles.

1. Fluorescence spectra from cancerous and normal human breast and lung tissues

2. Laser induced fluorescence spectroscopy from native cancerous and normal tissue

3. UV-fluorescence spectroscopic technique in the diagnosis of breast, ovarian, uterus, and cervix cancer

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