Positive views on antipsychotic long-acting injections: results of a survey of community patients prescribed antipsychotics

Author:

Mace Shubhra12ORCID,Chak Oscar3,Punny Sharanjeet3,Sedough-Abbasian Daniel3,Vegad Chirag4,Taylor David M.35

Affiliation:

1. Maudsley Hospital, Pharmacy Department, Denmark Hill, London SE5 8AZ, UK

2. Institute of Pharmaceutical Science, King’s College, London, 5th Floor, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UK

3. Maudsley Hospital, Pharmacy Department, Denmark Hill, London, UK

4. King’s College Hospital, Pharmacy Department, Denmark Hill, London, UK

5. Institute of Pharmaceutical Science, King’s College, London, UK

Abstract

Background: We aimed to assess patients’ views about antipsychotic long-acting injections (LAIs). Methods: We interviewed patients prescribed an antipsychotic (oral or LAI) in our community teams. In a subanalysis, responses were analysed for differences between patients currently receiving an LAI and those prescribed only oral medication. Results: In total, 226 patients (57%) completed the study questionnaire. The majority agreed that LAIs ensured delivery of the right amount of medication and protection against hospital admissions (57% and 60%, respectively). A minority of participants were more concerned than not about the use of a needle (46%), pain from injection (48%) and the need to travel to receive the injection (34%). A majority expressed a preference for injection site (deltoid or gluteal) (65%) and clinic location (69%). A higher proportion of patients currently receiving an LAI compared with those prescribed oral medication thought an LAI was beneficial because this formulation obviated the need to: swallow tablets (63% versus 41%; p = 0.0013), remember to take tablets daily (75% versus 51%; p = 0.0004), remember tablets when away from home (72% versus 49%; p = 0008). Current LAI users were more likely than those on oral treatment to agree that LAIs keep patients out of hospital (76% versus 44%; p = 0.0001) and that the injection ensured delivery of the right amount of medication (71% versus 44%; p = 0.0002). Women were more likely than men to prefer administration by a clinician of the same gender (34% versus 12%; p = 0.0001). Conclusions: In our study, a greater proportion of patients prescribed an LAI regarded LAIs as beneficial compared with those on oral medication.

Publisher

SAGE Publications

Subject

Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Psychology (miscellaneous)

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