The evaluation of Candida-related central line-related bloodstream infections in pediatric cancer patients: A pre- and post-intervention study-Reference-Cited by-同舟云学术

The evaluation of Candida-related central line-related bloodstream infections in pediatric cancer patients: A pre- and post-intervention study

Published:2023-08-26 Issue:5 Volume:24 Page:219-222
ISSN:1757-1774
Container-title:Journal of Infection Prevention
language:en
Short-container-title:Journal of Infection Prevention

Author:

Devrim İlker¹^ORCID,Celebi Miray Yılmaz²,Karakaya Nurgul¹,Sahinkaya Sahika²,Acar Sultan Okur¹,Cem Ela²,Demirağ Bengü¹,Oruc Yeliz²,Kara Aybuke Akaslan²,Oymak Yesim¹,Karapınar Tuba Hilkay¹,Bayram Nuri¹

Affiliation:

1. Department of Pediatric Hematology and Oncology, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey

2. Department of Pediatric Infectious Diseases, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey

Abstract

Aim/Objections The purpose of this study was to assess the efficacy of a central line maintenance bundle in preventing catheter-related (implanted venous access devices, port) Candida bloodstream infections. Methods The study encompassed two distinct time periods, namely, pre-bundle and bundle. The number of catheter-related bloodstream infections (CRBSI) episodes per catheter days for each timeframe was determined. Findings/Results Upon implementation of the central line bundle, the rate of CRBSI reduced significantly from 4.27 per 1000 central line days in the pre-bundle period to 1.0 per 1000 central line days in the bundle period ( p < .001). Discussion Using a central line bundle to avoid CRBSIs in pediatric cancer patients with ports led to a significant decrease in Candida species-related CRBSIs.

Publisher

SAGE Publications

Subject

Infectious Diseases,Advanced and Specialized Nursing,Public Health, Environmental and Occupational Health,Health Policy

Link

http://journals.sagepub.com/doi/pdf/10.1177/17571774231191334

Reference13 articles.

1. Elimination of Bloodstream Infections Associated with Candida albicans Biofilm in Intravascular Catheters

2. Preventive strategies for central line–associated bloodstream infections in pediatric hematopoietic stem cell transplant recipients

3. Central line bundle for prevention of central line–associated bloodstream infection for totally implantable venous access devices (ports) in pediatric cancer patients

4. Central line bundle including split-septum device and single-use prefilled flushing syringes to prevent port-associated bloodstream infections: a cost and resource-utilization analysis

5. Candida biofilms and their role in infection