The Role of Vitamin D in Human Health: A Paradigm Shift

Author:

Lappe Joan M.1

Affiliation:

1. Creighton University, Omaha, NE, USA,

Abstract

Vitamin D deficiency is pandemic, spanning many continents and including all ages, genders and racial/ethnic groups. Currently, world-wide attention is focused on the importance of vitamin D in optimizing health and preventing disease. This focus is largely the result of the scientific discovery that vitamin D receptors are present in nearly every tissue and cell in the body and that adequate vitamin D status is essential for optimal functioning of these tissues and cells. An impressive body of research has accumulated over the past two decades providing new information about the role of vitamin D in prevention of a broad range of diseases. The purpose of this paper is to provide a review of this new information.

Publisher

SAGE Publications

Subject

Fluid Flow and Transfer Processes,Building and Construction

Reference193 articles.

1. Stumpf W., Sar M., DeLuca H. Sites of action of 1,25(OH)D2 identified by thaw-mount autoradiography . In: Cohn D, Talmage R, Matthews K, eds. Hormonal Control of Calcium Metabolism. Amsterdam , Netherlands: Oxford-Princeton; 1981:222-229.

2. 25-Hydroxyvitamin D3-1α-hydroxylase and vitamin D receptor gene expression in human colonic mucosa is elevated during early cancerogenesis

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