Hemophagocytic Lymphohistiocytosis in a Patient With Angioimmunoblastic Lymphoma

Abstract

Hemophagocytic lymphohistiocytosis is a rare disorder characterized by a proliferation of phagocytic histiocytes in hematopoietic organs. It is accompanied by systemic manifestations and frequently has an abrupt onset with a fulminant clinical course and high mortality. Awareness of this condition is important since early diagnosis and initiation of treatment is critical for a successful outcome. The authors report a patient with hemophagocytic lymphohistiocytosis associated with angioimmunoblastic lymphoma, describe the clinical and histological features of hemophagocytic lymphohistiocytosis, and review the literature on this condition.