Polyps and Polypoid Lesions of the Colon

Abstract

Context. A significant portion of colorectal biopsies are performed for evaluation of polyps or polypoid lesions. Accurately identifying these lesions will promote better patient care. Objective. Review of the pathology of major colon polyps and polypoid lesions and highlight the most diagnostically useful features and their molecular biology. Data source. Review of recent literature. Conclusions. Polypoid lesions of the colon can be thought of to be under 3 broad categories: syndromic, mesenchymal, and epithelial.