Melanoma With Rhabdomyosarcomatous Differentiation-Reference-Cited by-同舟云学术

Melanoma With Rhabdomyosarcomatous Differentiation

Published:2014-04-29 Issue:6 Volume:22 Page:512-519
ISSN:1066-8969
Container-title:International Journal of Surgical Pathology
language:en
Short-container-title:Int J Surg Pathol

Author:

Shenjere Patrick¹,Fisher Cyril²,Rajab Ramzi³,Patnaik Lipsta⁴,Hazell Steve²,Thway Khin²

Affiliation:

1. Department of Histopathology, The Christie Hospital, Manchester, UK

2. Department of Histopathology, Royal Marsden Hospital, London, UK

3. Department of Cellular Pathology, St George’s Hospital, London, UK

4. Department of Pathology, Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, UK

Abstract

We describe 2 new cases of malignant melanoma with divergent rhabdomyoblastic differentiation occurring in adult patients. The patients were women aged 67 and 51 years with primary cutaneous and uterine cervical melanoma, respectively. Rhabdomyoblastic differentiation in melanoma is very rare in adult patients, and to our knowledge, only 7 such cases have been described in the world literature, of which only 4 have conclusive documentation of the presence of rhabdomyoblastic differentiation. We present the fifth and sixth cases of adult melanomas with conclusive divergent rhabdomyoblastic differentiation, including the first noncutaneous (cervical) case; we also review the literature and highlight the potential for underrecognition of this phenomenon.

Publisher

SAGE Publications

Subject

Pathology and Forensic Medicine,Surgery,Anatomy

Link

http://journals.sagepub.com/doi/pdf/10.1177/1066896914531817

Reference11 articles.

1. Desmoplastic Malignant Melanoma and Its Variants

2. Rhabdomyoblastic Differentiation in Malignant Melanoma in Adults: Report of 2 Cases

3. Malignant Melanoma with Metastatic Rhabdomyosarcomatoid Transdifferentiation

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