Review Article: Relationship of Human Papillomavirus With Papillary Squamous Cell Carcinoma of the Upper Aerodigestive Tract: A Review-Reference-Cited by-同舟云学术

Review Article: Relationship of Human Papillomavirus With Papillary Squamous Cell Carcinoma of the Upper Aerodigestive Tract: A Review

Published:2008-04 Issue:2 Volume:16 Page:127-136
ISSN:1066-8969
Container-title:International Journal of Surgical Pathology
language:en
Short-container-title:Int J Surg Pathol

Author:

Cobo Fernando¹,Talavera Paloma²,Concha Ángel²

Affiliation:

1. Infectious Pathology Unit, Department of Pathology and Tumour and Tissue Bank, Hospital Universitario Virgen de las Nieves, Granada, Spain,

2. Infectious Pathology Unit, Department of Pathology and Tumour and Tissue Bank, Hospital Universitario Virgen de las Nieves, Granada, Spain

Abstract

The purpose of this review is to evaluate case reports of papillary squamous cell carcinoma (PSCC) of the upper aerodigestive tract (UADT) to assess its relationship with human papillomavirus (HPV). The medical literature was searched for case reports of this condition. A total of 115 cases of PSCC were found that described the condition in sufficient detail. HPV detection was performed in only 22 of the 115 cases of PSCC (19%), and 11 of the 22 cases (50%) are related to this virus. The majority of cases related to HPV are produced by low-risk HPV type 6 followed by high-risk HPV type 16. Today, the association of HPV with PSCCs seems unclear because in the majority of patients tests were not performed for the detection of the HPV. This association should be clearly established to make a correct diagnosis and propose the best therapeutic strategies, such as new vaccines.

Publisher

SAGE Publications

Subject

Pathology and Forensic Medicine,Surgery,Anatomy

Link

http://journals.sagepub.com/doi/pdf/10.1177/1066896908314700

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