Hepatic Uterus-Like Mass Misdiagnosed as Hepatic Abscess

Author:

Sopha Sabrina C.1,Rosado Flavia G. N.2,Smith J. J.3,Merchant Nipun B.4,Shi Chanjuan4

Affiliation:

1. The Johns Hopkins Hospital, Baltimore, MD, USA

2. The Mayo Clinic, Rochester, MN, USA

3. Memorial Sloan-Kettering Cancer Center, New York, NY, USA

4. Vanderbilt University Medical Center, Nashville, TN, USA

Abstract

Background. Hepatic endometriosis/uterus-like mass is rare and may be overlooked during hepatic cyst workups. We report a case of uterus-like mass, misdiagnosed as hepatic abscess. Case Report: A 47-year-old woman developed abdominal pain and vomiting. Infectious colitis with hepatic abscess was diagnosed, and remained antibiotic-refractory. Fine-needle aspiration and core biopsies showed benign contents. The patient presented to our institution with symptoms and normal blood work. Laparoscopic excision demonstrated a 1.4-cm cyst composed of endometrial glands (estrogen receptor+ and progesterone receptor+) and stroma (CD10+) with smooth muscle actin (SMA+), arranged in an organoid fashion. The patient, status-post hysterectomy, had no history or symptoms of endometriosis. Conclusion. This rare case illustrates the merit of considering uterus-like mass/endometriosis in the differential diagnosis of antibiotic-refractory hepatic cysts. Cyst heterogeneity may confound needle biopsy. We report the first instance of a hepatic uterus-like mass, with a review of related entities, postulated histogenesis, and important clinical associations.

Publisher

SAGE Publications

Subject

Pathology and Forensic Medicine,Surgery,Anatomy

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