Wagner-Meissner–Like Corpuscles in Gastric Mucosa

Abstract

Wagner-Meissner corpuscles are touch receptors that are located in dermal papillae and are usually absent in gastrointestinal mucosa. Wagner-Meissner–like corpuscles have been reported in association with benign neural neoplasm. A case of Wagner-Meissner–like corpuscles in endoscopically normal gastric mucosa biopsy of a 48-year-old woman is presented here. The corpuscles were positive for S-100 and clinical evidence of neurofibromatosis was negative. From a review of the literature, only 2 cases of tactile corpuscle-like structures in gastric mucosa are available.