Composite Mucoepidermoid Carcinoma and Columnar Cell Variant of Papillary Carcinoma of the Thyroid-Reference-Cited by-同舟云学术

Composite Mucoepidermoid Carcinoma and Columnar Cell Variant of Papillary Carcinoma of the Thyroid

Published:2016-01-10 Issue:4 Volume:24 Page:336-340
ISSN:1066-8969
Container-title:International Journal of Surgical Pathology
language:en
Short-container-title:Int J Surg Pathol

Author:

Taconet Sarah¹²,Bosq Jacques¹,Hartl Dana³,Schlumberger Martin⁴⁵,Leboulleux Sophie⁴,Scoazec Jean-Yves¹⁵,Al-Ghuzlan Abir¹

Affiliation:

1. Service de Pathologie Morphologique, Gustave Roussy Cancer Campus, Villejuif, France

2. Universite Paris Nord Sorbonne Cite, UFR Médecine Santé Biologie humaine, Bobigny, France

3. Unité de chirurgie thyroïdienne, Gustave Roussy Cancer Campus, Villejuif, France

4. Service de médecine nucléaire, Gustave Roussy Cancer Campus, Villejuif, France

5. Université Paris Saclay, Université Paris Sud, Faculté de Médecine, Le Kremlin-Bicêtre, France

Abstract

Primary mucoepidermoid carcinoma (MEC) of the thyroid and columnar cell variant of papillary carcinoma of the thyroid (PCT) are uncommon neoplasms. We report the first case of composite MEC and columnar cell variant of PCT. An 86-year-old man consulted for a 47-mm thyroid nodule, cytologically compatible with PCT. Total thyroidectomy was performed. Histological diagnosis, with support of histochemistry and immunohistochemistry, was mixed primary carcinoma of the thyroid, associating an MEC component with predominantly columnar cell variant of PCT. Sixteen months after surgery and external beam radiation therapy, the patient was free of recurrence or distant metastasis. This case report offers an opportunity to highlight the potential pitfalls concerning the interpretation of mucin histochemistry in thyroid tumors.

Publisher

SAGE Publications

Subject

Pathology and Forensic Medicine,Surgery,Anatomy

Link

http://journals.sagepub.com/doi/pdf/10.1177/1066896915626281

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