1. Faculty of Health and Applied Sciences, University of the West of England, Bristol, UK
2. North Bristol NHS Trust, Bristol, UK
3. Faculty of Medicine, Department of Surgery & Cancer, Imperial College London, London, UK
4. Warwick Clinical Trials Unit, University of Warwick, Coventry, UK
5. University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
6. Intensive Care National Audit and Research Centre (ICNARC), London, UK
7. Royal United Hospitals Bath NHS Foundation Trust, Bath, UK
8. University Hospitals Bristol NHS Foundation Trust, Bristol, UK