Intravenous Lipid Emulsion (ILE) Therapy for Severe Felodipine Toxicity-Reference-Cited by-同舟云学术

Intravenous Lipid Emulsion (ILE) Therapy for Severe Felodipine Toxicity

Published:2013-10 Issue:4 Volume:14 Page:346-348
ISSN:1751-1437
Container-title:Journal of the Intensive Care Society
language:en
Short-container-title:Journal of the Intensive Care Society

Author:

Barnicott Lee RC¹,Tarmey Nick T²,Craig Gordon R²,Thomas Simon HL³

Affiliation:

1. CT2, Department of Critical Care, Portsmouth Hospitals NHS Trust, Queen Alexandra Hospital, Portsmouth

2. Consultant, Department of Critical Care, Queen Alexandra Hospital, Portsmouth

3. Director, National Poisons Information Service (Newcastle) Unit, Wolfson Unit of Clinical Pharmacology, Newcastle

Abstract

Intravenous lipid emulsion (ILE) is increasingly used for the treatment of poisoning caused by lipid-soluble drugs. We report a case of reversal of cardiovascular collapse after the use of ILE in a patient with a mixed overdose, mainly of the calcium channel blocker felodipine. Conclusions that can be drawn from a single case are limited, but this report provides circumstantial evidence of benefit of ILE for felodipine poisoning. The use of ILE appears justified in cases refractory to conventional therapy.

Publisher

SAGE Publications

Subject

Critical Care and Intensive Care Medicine,Critical Care

Link

http://journals.sagepub.com/doi/pdf/10.1177/175114371301400415

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