Affiliation:
1. Artificial Cells and Organs Research Centre Faculty of Medicine, McGill University Montreal, PQ, Canada
Abstract
Suspension of living hepatocytes were microencapsulated inside 300 micron mean diameter alginate artificial cells. The galactosamine fulminant hepatic failure rat model was used. 48 hours after the injection of galactosamine, grade II coma hepatic failure rats were divided into pairs. One of the pair was randomly chosen for the control group, and the other for the treated group. Each rat in the control group received one peritoneal injection of microcapsules containing no hepatocytes. Each rat in the treated group received one peritoneal injection of microcapsules containing hepatocytes. The survival of the treated group is significantly higher than the control group.
Subject
Biomedical Engineering,Biomaterials,General Medicine,Medicine (miscellaneous),Bioengineering
Cited by
131 articles.
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