Serum Vitamin E Levels in Patients with Chronic Renal Failure

Author:

Stein G.1,Richter G.1,Fünfstück R.1,Sperschneider H.1,Günther K.1

Affiliation:

1. Division of Nephrology, Clinic of Internal Medicine, Friedrich-Schiller-University, Jena-Lobeda, Department of Animal Nutrition, Karl-Marx-University Jena, GDR

Abstract

27 patients with chronic renal failure, 21 patients on chronic intermittend dialysis treatment and 27 healthy controls were tested for serum level of vitamin E estimated spectrophotometrically. Both patient groups had significant higher mean values (12.1 ± 1.2 and 7.2 ± 0.8 μg/ml respectively) in comparison with normal controls (4.6 ± 0.7 μg/ml). No correlation was found to serum creatinine, hematologic values, protein and lipoprotein concentration, nor to mode and duration of treatment regimes. Vitamin E was not extracted from blood throughout dialysis. Under normal conditions of conservative or dialysis treatment of chronic renal failure patients vitamin E seems not to be a factor concerning uremic symptoms and there is no need for supplementation.

Publisher

SAGE Publications

Subject

Biomedical Engineering,Biomaterials,General Medicine,Medicine (miscellaneous),Bioengineering

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