Ginsenoside Rb1 Enhances Peripheral Nerve Regeneration across Wide Gaps in Silicone Rubber Chambers-Reference-Cited by-同舟云学术

Ginsenoside Rb1 Enhances Peripheral Nerve Regeneration across Wide Gaps in Silicone Rubber Chambers

Published:2002-11 Issue:11 Volume:25 Page:1103-1108
ISSN:0391-3988
Container-title:The International Journal of Artificial Organs
language:en
Short-container-title:Int J Artif Organs

Author:

Chen Y.-S.¹,Wu C.-H.¹,Yao C.-H.²,Chen C.-T.³

Affiliation:

1. Laboratory of Biomaterials, Institute of Chinese Medical Science, China Medical College, Taichung - Taiwan

2. Department of Radiological Technology, Chung-Tai Institute of Health Science and Technology, Taichung - Taiwan

3. Taipei Municipal Hospital of Traditional Chinese Medicine, Taipei - Taiwan

Abstract

Silicone rubber chambers filled with collagen containing ginsenoside Rb1 (GRb1) were used to repair lesioned rat sciatic nerves with 15-mm gaps between stumps. Six weeks after implantation, histology of the nerve regenerated in the chambers filled with GRb1 and collagen contained larger axons than those in the chambers with collagen only. This study showed that the GRb1 could exert a positive influence on nerve regeneration when using silicone rubber tubes.

Publisher

SAGE Publications

Subject

Biomedical Engineering,Biomaterials,General Medicine,Medicine (miscellaneous),Bioengineering

Link

http://journals.sagepub.com/doi/pdf/10.1177/039139880202501110

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