Hemoperfusion with a New Anion Exchange Resin Corrects the Metabolic Alkalosis in Pyloric Stenosis: An Experimental Demonstration-Reference-Cited by-同舟云学术

Hemoperfusion with a New Anion Exchange Resin Corrects the Metabolic Alkalosis in Pyloric Stenosis: An Experimental Demonstration

Published:1992-11 Issue:11 Volume:15 Page:677-680
ISSN:0391-3988
Container-title:The International Journal of Artificial Organs
language:en
Short-container-title:Int J Artif Organs

Author:

Faenza S.¹,Balestri M.¹,Martinelli G.¹,Spighi M.¹,Fini M.²,Giardino R.²,Colì L.³,Cianciolo G.³,Stefoni S.³,Bonomini V.³

Affiliation:

1. Anaesthesiology Institute, S. Orsola Hospital, Bologna - Italy

2. Department of Experimental Surgery, Rizzoli Orthopaedic Institute, Bologna - Italy

3. Nephrology Department, S. Orsola Hospital, Bologna - Italy

Abstract

An experimental model of hypertrophic pyloric stenosis was made by suture of the pyloric wall and gastrostomy in 10 rabbits under general anesthesia. Blood sampling indicated severe alkalosis and hypochloremia 3h 30 min after surgery. To correct the derangement, we tested an ion exchange resin (Dowex SAR), coated with a methacrylic hydrogel. A cartridge containing 18 g of this resin was inserted in an extracorporeal circuit. This chloride charged resin achieved uptake of HCO−3 ions, and elution of CI− ions. The electrolytic balance was fully restored after 10 min of treatment.

Publisher

SAGE Publications

Subject

Biomedical Engineering,Biomaterials,General Medicine,Medicine (miscellaneous),Bioengineering

Link

http://journals.sagepub.com/doi/pdf/10.1177/039139889201501111

Reference12 articles.

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2. The management of hypertrophic pyloric stenosis at the Los Angeles Childrens Hospital

3. Water, Sodium and Acid-Base Balance in Premature Infants: Therapeutical Aspects

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