Deep grey matter `black T2` on 3 tesla magnetic resonance imaging correlates with disability in multiple sclerosis-Reference-Cited by-同舟云学术

Deep grey matter `black T2` on 3 tesla magnetic resonance imaging correlates with disability in multiple sclerosis

Published:2007-04-27 Issue:7 Volume:13 Page:880-883
ISSN:1352-4585
Container-title:Multiple Sclerosis Journal
language:en
Short-container-title:Mult Scler

Author:

Zhang Y.¹,Zabad RK²,Wei X.³,Metz LM²,Hill MD²,Mitchell JR⁴

Affiliation:

1. Department of Radiology, University of Calgary, Calgary T2N 2T9, Canada, Hotchkiss Brain Institute, University of Calgary, Calgary T2N 2T9, Canada

2. Hotchkiss Brain Institute, University of Calgary, Calgary T2N 2T9, Canada, Department of Clinical Neurosciences, University of Calgary, Calgary T2N 2T9, Canada th

3. Department of Radiology, University of Calgary, Calgary T2N 2T9, Canada

4. Department of Radiology, University of Calgary, Calgary T2N 2T9, Canada, Hotchkiss Brain Institute, University of Calgary, Calgary T2N 2T9, Canada, Department of Clinical Neurosciences, University of Calgary, Calgary T2N 2T9, Canada,

Abstract

T2 hypointensity (black T2, BT2) in the deep grey matter of multiple sclerosis (MS) patients correlate weakly with disability at 1.5 T. BT2 is likely to be caused by abnormal iron deposition. We compared the correlation between disability and deep grey matter BT2 measured on 3 T MRI and on 1.5 T MRI in 17 MS patients. We observed a significant correlation between expanded disability status scale and signal intensity on 3 T MRI in the globus pallidus and the caudate nucleus ( r = —0.5, P < 0.05). BT2 at 3 T may be a useful MRI measure associated with disability in MS and warrants further study. Multiple Sclerosis 2007; 13: 880—883. http://msj.sagepub.com

Publisher

SAGE Publications

Subject

Clinical Neurology,Neurology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1352458507076411

Reference13 articles.

1. T2 Hypointensity in the Deep Gray Matter of Patients With Multiple Sclerosis

2. Biological Significance of Iron-Related Magnetic Resonance Imaging Changes in the Brain

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