Neuromyelitis optica spectrum disorder mimicking extensive leukodystrophy

Author:

Ciron Jonathan1,Colin Olivier2,Rosier Marie-Pierre3,Lapeyrie Soline2,Biotti Damien4,Brassat David4,Neau Jean-Philippe2

Affiliation:

1. Department of Neurology, CHU Toulouse, Toulouse, France/Department of Neurology, CHU Poitiers, Poitiers, France

2. Department of Neurology, CHU Poitiers, Poitiers, France

3. Department of Neurology, CH Niort, Niort, France

4. Department of Neurology, CHU Toulouse, Toulouse, France

Abstract

Brain MRI was originally considered to appear normal in neuromyelitis optica spectrum disorders (NMO-SD). Typical brain lesions are now well described and have been integrated in the latest revision of NMO-SD criteria, but the NMO-SD MRI pattern remains not yet comprehensive. We report here extensive white matter lesions (EWML) mimicking leukodystrophy in a 50-year-old woman with long-lasting anti-AQP4+ NMO-SD. We suggest that EWML could be a possible brain MRI presentation of NMO-SD patients.

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

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