Observatoire Français de la Sclérose en Plaques (OFSEP): A unique multimodal nationwide MS registry in France-Reference-Cited by-同舟云学术

Observatoire Français de la Sclérose en Plaques (OFSEP): A unique multimodal nationwide MS registry in France

Published:2018-12-13 Issue:1 Volume:26 Page:118-122
ISSN:1352-4585
Container-title:Multiple Sclerosis Journal
language:en
Short-container-title:Mult Scler

Author:

Vukusic Sandra¹^ORCID,Casey Romain¹,Rollot Fabien¹,Brochet Bruno²,Pelletier Jean³,Laplaud David-Axel⁴,De Sèze Jérôme⁵,Cotton François⁶,Moreau Thibault⁷,Stankoff Bruno⁸,Fontaine Bertrand⁹,Guillemin Francis¹⁰,Debouverie Marc¹¹,Clanet Michel¹²

Affiliation:

1. Service de neurologie—sclérose en plaques, pathologies de la myéline et neuro-inflammation, Hôpital Pierre Wertheimer, Hospices Civils de Lyon, Bron, France/Observatoire Français de la Sclérose en Plaques, Centre de Recherche en Neurosciences de Lyon, INSERM 1028 et CNRS UMR 5292, F-69003 Lyon, France/Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France/ Eugène Devic EDMUS Foundation against Multiple Sclerosis, Bron, France

2. Service de Neurologie, CHU de Bordeaux, Bordeaux, France/Université de Bordeaux, Bordeaux, France/INSERM U 1215, Neurocentre Magendie, Bordeaux, France

3. Service de Neurologie, Pôle de Neurosciences Cliniques, Hôpital de la Timone, APHM and CNRS, CRMBM UMR 7339, Aix-Marseille Université, Marseille, France

4. Service de Neurologie, Centre Hospitalier Universitaire de Nantes and CIC015 INSERM, Nantes, France/INSERM CR1064, Nantes, France

5. Department of Neurology and Clinical Investigation Center, CHU de Strasbourg, INSERM 1434, Strasbourg, France

6. Department of Radiology, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, Pierre-Bénite, France/ CREATIS, CNRS UMR 5220, INSERM U1044, Villeurbanne, France/ Université Lyon 1, Lyon, France

7. Department of Neurology, CHU de Dijon, EA7270, University Bourgogne Franche-Comté, Dijon, France

8. Neurology Department, Hôpital Saint-Antoine, APHP, Paris, France

9. INSERM UMR S 1127, CNRS UMR 7225, Institut du Cerveau et de la Moelle épinière (ICM), Hôpital de la Pitié Salpêtrière, Sorbonne Universités, UPMC Paris 06, Paris, France

10. EA 4360 APEMAC, Université de Lorraine, Nancy, France/INSERM CIC 1433 Clinical Epidemiology, Nancy University Hospital, Nancy, France

11. EA 4360 APEMAC, Université de Lorraine, Nancy, France/Department of Neurology, Nancy University Hospital, Nancy, France

12. Department of Neurology, CHU de Toulouse, Toulouse, France

Abstract

The care of multiple sclerosis (MS) in France is based on two complementary interlinked networks: MS expert centers in university hospitals and regional networks of neurologists. The routine use of European database for multiple sclerosis (EDMUS) in all those centers has paved the way for the constitution of a national registry, designated as Observatoire Français de la Sclérose En Plaques (OFSEP). It promotes a prospective, standardized, high-quality, and multimodal collection of data. On June 2018, there were 68.097 files, with 71.1% females, representing 761,185 person-years. This huge database is open to the scientific community and might contribute exploring unresolved issues and unmet needs in MS.

Funder

Agence Nationale de la Recherche

Publisher

SAGE Publications

Subject

Clinical Neurology,Neurology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1352458518815602

Reference10 articles.

1. EDMUS, a European database for multiple sclerosis.

2. OFSEP, a nationwide cohort of people with multiple sclerosis: Consensus minimal MRI protocol

3. Comparative efficacy of fingolimod vs natalizumab