Adverse events after endovascular treatment of chronic cerebro-spinal venous insufficiency (CCSVI) in patients with multiple sclerosis-Reference-Cited by-同舟云学术

Adverse events after endovascular treatment of chronic cerebro-spinal venous insufficiency (CCSVI) in patients with multiple sclerosis

Published:2013-02-04 Issue:7 Volume:19 Page:961-963
ISSN:1352-4585
Container-title:Multiple Sclerosis Journal
language:en
Short-container-title:Mult Scler

Author:

Ghezzi A¹,Annovazzi P¹,Amato MP²,Capello E³,Cavalla P⁴,Cocco E⁵,Falcini M⁶,Gallo A⁷,Patti F⁸,Perini P⁹,Rodegher ME¹⁰,Rovaris M¹¹,Rottoli MR¹²,Comi G¹¹⁰,

Affiliation:

1. Centro Studi Sclerosi Multipla, Ospedale di Gallarate, Italy

2. Department of Neurosciences — University of Florence, Italy

3. Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova

4. Clinica Neurologica, Università di Torino, Italy

5. Centro Sclerosi Multipla, Dipartimento di Sanità Pubblica, Medicina Clinica e Molecolare, University of Cagliari, Italy

6. Multiple Sclerosis Center, Ospedale Misericordia e Dolce, Italy

7. Multiple Sclerosis Centre, I Division of Neurology, Second University of Naples, Italy

8. DANA GF Ingrassia, Neuroscience Section, Multiple Sclerosis Center, University of Catania, Italy

9. Neurological Department, Azienda Ospedaliera Università di Padova, Italy

10. Department of Neurology, Vita-Salute San Raffaele University, San Raffaele Scientific Institute, Italy

11. Multiple Sclerosis Center, Fondazione Don Gnocchi, Italy

12. Multiple Sclerosis Center, Dipartimento di Chirurgia del Sistema Nervoso e Neuroscienze, Ospedali Riuniti Bergamo, Italy

Abstract

Although it is debated whether chronic cerebro-spinal venous insufficiency (CCSVI) plays a role in multiple sclerosis (MS) development, many patients undergo endovascular treatment (ET) of CCSVI. A study is ongoing in Italy to evaluate the clinical outcome of ET. Severe adverse events (AEs) occurred in 15/462 subjects at a variable interval after ET: jugular thrombosis in seven patients, tetraventricular hydrocephalus, stroke, paroxysmal atrial fibrillation, status epilepticus, aspiration pneumonia, hypertension with tachicardia, or bleeding of bedsore in the remaining seven cases. One patient died because of myocardial infarction 10 weeks after ET. The risk of severe AEs related to ET for CCSVI must be carefully considered.

Publisher

SAGE Publications

Subject

Clinical Neurology,Neurology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1352458513475491

Reference8 articles.

1. A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency

2. Endovascular treatment for chronic cerebrospinal venous insufficiency: is the procedure safe?

3. Safety Profile of Endovascular Treatment for Chronic Cerebrospinal Venous Insufficiency in Patients With Multiple Sclerosis

4. Safety of Endovascular Treatment of Chronic Cerebrospinal Venous Insufficiency: A Report of 240 Patients with Multiple Sclerosis

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