Reappraisal of CSF-specific oligoclonal bands in Asia-Reference-Cited by-同舟云学术

Reappraisal of CSF-specific oligoclonal bands in Asia

Published:2021-10-06 Issue: Volume: Page:135245852110487
ISSN:1352-4585
Container-title:Multiple Sclerosis Journal
language:en
Short-container-title:Mult Scler

Author:

Kim Ki Hoon¹²^ORCID,Kim Su-Hyun²,Park Na Young²,Hyun Jae-Won²^ORCID,Kim Ho Jin²^ORCID

Affiliation:

1. Department of Neurology, Research Institute and Hospital, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang 10408, Korea

2. Department of Neurology, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Abstract

The prevalence of cerebrospinal fluid–specific oligoclonal bands (CSF-OCBs) was reported to be low in Asian people with multiple sclerosis (pwMS) compared to that in Western pwMS. It is yet to be determined whether it is a genuine feature of Asian pwMS or a misapprehension owing to past mis-classification of MS-mimicking diseases as MS. We aimed to reappraise the prevalence of CSF-OCBs in Korean pwMS after carefully excluding other central nervous system-inflammatory demyelinating diseases since 2017. Among 88 subjects, 78 (88.6%) were positive for CSF-OCBs, which suggests the prevalence of CSF-OCBs is not different between Korean and Western pwMS.

Funder

the National Research Foundation of Korea

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

Link

http://journals.sagepub.com/doi/pdf/10.1177/13524585211048752

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