A multicenter randomized controlled trial of two group education programs for fatigue in multiple sclerosis: Long-term (12-month) follow-up at one site-Reference-Cited by-同舟云学术

A multicenter randomized controlled trial of two group education programs for fatigue in multiple sclerosis: Long-term (12-month) follow-up at one site

Published:2018-05-15 Issue:6 Volume:25 Page:871-875
ISSN:1352-4585
Container-title:Multiple Sclerosis Journal
language:en
Short-container-title:Mult Scler

Author:

Hugos Cinda L¹,Cameron Michelle H¹,Chen Zunqiu²,Chen Yiyi²,Bourdette Dennis¹

Affiliation:

1. VA Portland Health Care System, Oregon Health and Sciences University, Portland, OR, USA

2. OHSU Biostatistics Design Program, OHSU-PSU School of Public Health, Oregon Health and Sciences University, Portland, OR, USA

Abstract

Background: A four-site RCT of Fatigue: Take Control (FTC), a multicomponent group program, found no significant differences from a control program, MS: Take Control (MSTC), in fatigue on the Modified Fatigue Impact Scale (MFIS) through 6 months. Objective: Assess FTC for a delayed effect on fatigue. Methods: Of 78 subjects at one site, 74 randomized to FTC or MSTC completed the MFIS at 12 months. Results: Compared to baseline, FTC produced greater improvements in MFIS scores than MSTC (FTC −8.9 (confidence interval (CI): 32.2, 45), MSTC −2.5 (CI 39.6, 47.7), p = 0.03) at 12 months. Conclusion: The delayed effect of FTC on fatigue suggests the need for longer follow-up when assessing interventions for fatigue.

Funder

Oregon Clinical and Translational Research Institute

U.S. Department of Veterans Affairs

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1352458518775920

Reference10 articles.

1. One year follow-up of a pragmatic multi-centre randomised controlled trial of a group-based fatigue management programme (FACETS) for people with multiple sclerosis

2. A multicenter randomized controlled trial of two group education programs for fatigue in multiple sclerosis: Short- and medium-term benefits

3. Interrater variability with the Expanded Disability Status Scale (EDSS) and Functional Systems (FS) in a multiple sclerosis clinical trial

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A multisite randomized controlled trial of two group education programs for fatigue in multiple sclerosis: Very long term (5–6 year) follow-up at one site;Multiple Sclerosis Journal - Experimental, Translational and Clinical;2021-10

2. Which exercise and behavioural interventions show most promise for treating fatigue in multiple sclerosis? A network meta-analysis;Multiple Sclerosis Journal;2021-04-20

3. Which behavioural and exercise interventions targeting fatigue show the most promise in multiple sclerosis? A systematic review with narrative synthesis and meta-analysis;Behaviour Research and Therapy;2021-02

4. MS Spasticity: Take Control (STC) for ambulatory adults: protocol for a randomized controlled trial;BMC Neurology;2020-10-07