Impact of depression and disability on quality of life in Iranian patients with multiple sclerosis

Author:

Ayatollahi P1,Nafissi S1,Eshraghian MR2,Kaviani H3,Tarazi A1

Affiliation:

1. Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran 14114, Iran

2. Department of Biostatistics and Epidemiology, Tehran University of Medical Sciences, Tehran 14176, Iran

3. Psychiatry and Psychology Research Center, Rouzbeh Hospital, Tehran University of Medical Sciences, Tehran 13185, Iran

Abstract

Multiple sclerosis (MS) can influence all aspects of a patient's health. This study determines the main factors affecting quality of life (QoL) in Iranian MS patients. QoL (Multiple Sclerosis Impact Scale; MSIS-29), disability (Expanded Disability Status Scale; EDSS) and depression (Beck Depression Inventory; BDI) were assessed in 106 MS patients. EDSS, clinical course and MS duration significantly correlated with physical MSIS-29. Depression highly correlated with both physical and psychological MSIS-29. Regression analyses showed that depression and EDSS predicted physical health. Psychological health was predicted by depression. These findings highlight that depression and physical disability strongly influence QoL in Iranian MS patients. Multiple Sclerosis 2007; 13: 275–277. http://msj.sagepub.com

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

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