Productivity loss among people with early multiple sclerosis: A Canadian study

Author:

Rodriguez Llorian Elisabet1ORCID,Zhang Wei2,Khakban Amir1,Patten Scott3,Traboulsee Anthony4,Oh Jiwon5,Kolind Shannon4,Prat Alexandre6,Tam Roger7,Lynd Larry D8

Affiliation:

1. Collaboration for Outcomes Research and Evaluation (CORE), Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, BC, Canada

2. School of Population and Public Health, The University of British Columbia, Vancouver, BC, Canada/Centre for Health Evaluation and Outcome Sciences (CHÉOS), St. Paul’s Hospital, Vancouver, BC, Canada

3. Department of Psychiatry, University of Calgary, Calgary, AB, Canada

4. Division of Neurology, Department of Medicine, The University of British Columbia, Vancouver, BC, Canada

5. Division of Neurology, St. Michael’s Hospital, University of Toronto, Toronto, ON, Canada

6. Department of Neurology, Faculty of Medicine, Université de Montreal, Montreal, QC, Canada

7. Department of Radiology and School of Biomedical Engineering, The University of British Columbia, Vancouver, BC, Canada

8. Collaboration for Outcomes Research and Evaluation (CORE), Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, BC, Canada/Centre for Health Evaluation and Outcome Sciences (CHÉOS), St. Paul’s Hospital, Vancouver, BC, Canada

Abstract

Objectives: To analyze work productivity loss and costs, including absenteeism (time missed from work), presenteeism (reduced productivity while working), and unpaid work loss, among a sample of employed people with multiple sclerosis (pwMS) in Canada, as well as its association with clinical, sociodemographic, and work-related factors. Methods: We used cross-sectional data collected as part of the Canadian Prospective Cohort Study to Understand Progression in MS (CanProCo) and information from the Valuation of Lost Productivity questionnaire. Results: Among 512 pwMS who were employed, 97% showed no or mild disability and 55% experienced productivity loss due to MS in the prior 3 months. Total productivity time loss over a 3-month period averaged 60 hours (SD = 107; 23 from presenteeism, 19 from absenteeism, and 18 from unpaid work), leading to a mean cost of lost productivity of CAD$2480 (SD = 4282) per patient, with an hourly paid productivity loss greater than the wage loss. Fatigue retained significant associations with all productivity loss outcomes. Conclusion: Unpaid work loss and productivity losses exceeding those of the employee alone (due to teamwork and associated factors) are key additional contributors of the high economic burden of MS. Workplace accommodations and treatments targeted at fatigue could lessen the economic impact of MS.

Funder

Multiple Sclerosis Society of Canada

Government of Alberta

Roche

Biogen-Idec

Brain Canada

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

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