Pencil-thin ependymal enhancement in neuromyelitis optica spectrum disorders

Author:

Banker Piyush1,Sonni Smitha1,Kister Ilya2,Loh John P3,Lui Yvonne W3

Affiliation:

1. Department of Radiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA

2. NYU-MS Center, Department of Neurology, New York University School of Medicine, NY, USA

3. Department of Radiology, New York University School of Medicine, NY, USA

Abstract

AQP4 water channels are thought to be the target of autoimmune attack in neuromyelitis optica-spectrum disorders (NMOsd). AQP4 are highly expressed on ventricular ependyma. The objective of this study was to describe a novel pattern of linear, ‘pencil-thin’ enhancement of ventricular ependyma in NMOsd. We report two NMOsd patients with pencil-thin ependymal enhancement along the frontal and occipital horns of lateral ventricles. Differential diagnosis of ependymal enhancement should include NMOsd alongside with infectious and neoplastic etiologies. Pencil-thin ependymal enhancement may be a helpful radiological marker of NMOsd that can be used to differentiate this condition from multiple sclerosis.

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

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