An early case of neuromyelitis optica: on a forgotten report by Jacob Lockhart Clarke, FRS

Author:

Jarius S1,Wildemann B1

Affiliation:

1. Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Germany.

Abstract

We discuss a forgotten report by the famous British neuroanatomist, neuropathologist and neurologist Jacob Augustus Lockhart Clarke (1817–1880) about a 17-year-old girl with bilateral optic neuritis and longitudinally extensive transverse myelitis. This report, which appeared in 1865, i.e. 15 years prior to Wilhelm Erb’s much-cited paper on the coincidence of optic neuritis and acute myelitis, represents the first known account of a case of Devic’s syndrome or neuromyelitis optica in the English-language medical literature.

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

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