Longitudinal personality change associated with cognitive decline in multiple sclerosis-Reference-Cited by-同舟云学术

Longitudinal personality change associated with cognitive decline in multiple sclerosis

Published:2018-01-24 Issue:14 Volume:24 Page:1909-1912
ISSN:1352-4585
Container-title:Multiple Sclerosis Journal
language:en
Short-container-title:Mult Scler

Author:

Roy Shumita¹,Drake Allison¹,Fuchs Tom²,Dwyer Michael G³,Zivadinov Robert³,Chapman Benjamin P⁴,Weinstock-Guttman Bianca¹,Benedict Ralph HB¹

Affiliation:

1. Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York (SUNY), Buffalo, NY, USA

2. Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York (SUNY), Buffalo, NY, USA/Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York (SUNY), Buffalo, NY, USA

3. Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York (SUNY), Buffalo, NY, USA/Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York (SUNY), Buffalo, NY, USA/Center for Biomedical Imaging at Clinical Translational Science Institute, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The...

4. Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA

Abstract

We previously reported that personality and cognition were stable over 3 years in patients with multiple sclerosis (MS). This study examined whether a longer duration would reveal evidence of emerging personality dysfunction. The NEO Five-Factor Inventory and Brief International Cognitive Assessment for MS was used to assess personality and cognition, respectively. Patients were classified as “Cog Stable” or “Cog Decline” based on cognitive deterioration over 5 years. Extraversion and Conscientiousness declined across pooled groups. Follow-up of a group by time interaction found that decline in these traits was more evident in the Cog Decline group, demonstrating a link between personality and cognitive change.

Funder

National Multiple Sclerosis Society

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1352458517753720

Reference12 articles.

1. Trait neuroticism, extraversion, and conscientiousness in multiple sclerosis: Link to cognitive impairment?

2. Influence of Personality on the Relationship Between Gray Matter Volume and Neuropsychiatric Symptoms in Multiple Sclerosis

3. Cortical atrophy and personality in multiple sclerosis.