1. Department of Neurology, Tohoku University School of Medicine, Sendai, Japan
2. Department of Neurology, Tohoku University School of Medicine, 1-1 Seiryomachi, Aobaku, Sendai, Japan
3. Department of Neurology, Tohoku University School of Medicine, Sendai, Japan/Department of Multiple Sclerosis Therapeutics, Tohoku University Graduate School of Medicine, Sendai, Japan