Uveitis as a prognostic factor in multiple sclerosis

Author:

Shugaiv Erkingul1,Tüzün Erdem2,Kürtüncü Murat1,Kıyat-Atamer Aslı3,Çoban Arzu1,Akman-Demir Gulsen3,Tugal-Tutkun Ilknur1,Eraksoy Mefkure1

Affiliation:

1. Istanbul Faculty of Medicine, Istanbul University, Turkey

2. Istanbul Faculty of Medicine, Istanbul University, Turkey/Institute for Experimental Medicine (DETAE), Istanbul University, Turkey

3. Faculty of Medicine, Istanbul Bilim University, Turkey

Abstract

Uveitis is occasionally encountered in multiple sclerosis (MS) patients. The objective of this report is to investigate whether uveitis has a prognostic impact on the clinical course of MS. Several clinical and demographic features were compared between 41 MS patients with uveitis and 100 randomly selected MS patients without uveitis. While there were no significant differences by means of gender, age of MS onset, oligoclonal band positivity and disease duration, EDSS and progression index (PI) scores of MS patients with uveitis were significantly lower than those without uveitis ( p = 0.004 and <0.001, respectively). Our results suggest that uveitis might be used as a good prognostic factor.

Publisher

SAGE Publications

Subject

Clinical Neurology,Neurology

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