A New Antibacterial Polyketide from the Endophytic Fungi Aspergillus fumigatiaffinis-Reference-Cited by-同舟云学术

A New Antibacterial Polyketide from the Endophytic Fungi Aspergillus fumigatiaffinis

Published:2018-12 Issue:12 Volume:13 Page:1934578X1801301
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Ola Antonius R. B.¹²,Tawo Bibiana D¹,Belli Henderiana L. L²,Proksch Peter³,Tommy Dhana³,Hakim Euis Holisotan⁴

Affiliation:

1. Department of Chemistry, Faculty of Science and Engineering

2. Integrated Center Research (Bioscience) Laboratory, Nusa Cendana University, Jl. Adisucipto Penfui, 85001 Kupang, Indonesia

3. Institut für Pharmazeutische Biologie und Biotechnologie, Heinrich-Heine-Universität, Universitätsstrasse 1, 40225 Düsseldorf, Germany

4. Department of Chemistry, Institute of Technology Bandung, Jl. Ganesha 10, Bandung 40132, Indonesia

Abstract

A new antibacterial polyketide (-) palitantin was isolated from Aspergillus fumigatiaffnis, an endophytic fungi from a medicinal plant Tribulus terestris. The structure of the antibacterial metabolite was established using 1D and 2D NMR together with mass spectroscopy. (-) Palitantin was found to inhibit the growth of Enterococcus faecalis UW 2689 and Streptococcus pneumoniae with MIC value of 64μg/mL.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1801301202

Reference9 articles.

1. Endophytic Fungi—Alternative Sources of Cytotoxic Compounds: A Review

2. Structural revision and absolute configuration of lateritin

3. New Anthracene Derivatives - Structure Elucidation and Antimicrobial Activity

4. Atropisomeric Dihydroanthracenones as Inhibitors of Multiresistant Staphylococcus aureus

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