Chemical Composition and Antibacterial Activity of the Essential Oil of Ruilopezia bracteosa

Author:

Alarcón Libia1,Peña Alexis1,Velasco Judith2,Baptista José Gregorio1,Rojas Luis3,Aparicio Rosa3,Usubillaga Alfredo3

Affiliation:

1. Departamento de Química. Grupo de investigación GIPRONA. Núcleo Universitario Rafael Rangel, Universidad de Los Andes, Trujillo, Venezuela

2. Departamento de Microbiología y Parasitología, Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, Venezuela

3. Instituto de Investigación, Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, Venezuela

Abstract

The essential oil from the leaves of Ruilopezia bracteosa was obtained by hydrodistillation, and analyzed by GC-MS. Eighteen components, which made up 99.6% of the oil were identified, the most abundant being β-myrcene (34.2%), α-pinene (24.3%), 7-epi-α-selinene (9.1%), β-pinene (8.5%) and 6,9-guaiadiene (4.4%). Antibacterial activity was tested against Gram-positive and Gram-negative bacteria using broth microdilution and disk agar diffusion methods. MIC values found presented significant differences between both methods, which may be due to diffusion factors.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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