Identification of Glycyrrhiza Species by Direct Analysis in Real Time Mass Spectrometry-Reference-Cited by-同舟云学术

Identification of Glycyrrhiza Species by Direct Analysis in Real Time Mass Spectrometry

Published:2010-11 Issue:11 Volume:5 Page:1934578X1000501
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Fukuda Eriko¹,Baba Masaki¹,Iwasaki Noriaki¹,Uesawa Yoshihiro²,Arifuku Kazunori³,Kamo Osamu³,Tsubono Koji³,Okada Yoshihito¹

Affiliation:

1. Department of Natural Medicine and Phytochemistry, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan

2. Department of Clinical Pharmaceutics, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan

3. JEOL LTD., 1156 Nakagami-cho, Akishima, Tokyo 196–0022, Japan

Abstract

DART (Direct Analysis in Real Time)-MS is a novel mass spectrometric ion source, and allows the analysis of most compounds at ambient pressure and ground potential by producing [M+H]+ molecular ion species. Using this method, we examined the compounds characteristic of several kinds of licorices. For the analysis of Glycyrrhiza inflata Batalin, the peak at m/z 339 originates mainly from [M+H]+ of licochalcone A (LA), a species-specific compound. This peak was hardly detected in G. glabra Linné and G. uralensis Fischer. These results indicate that G. inflata can be differentiated from the other two species by detection of LA peaks using DART-MS analysis.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1000501111

Reference9 articles.

1. Combining Two-Dimensional Diffusion-Ordered Nuclear Magnetic Resonance Spectroscopy, Imaging Desorption Electrospray Ionization Mass Spectrometry, and Direct Analysis in Real-Time Mass Spectrometry for the Integral Investigation of Counterfeit Pharmaceuticals

2. Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions

3. Elderberry flavonoids bind to and prevent H1N1 infection in vitro

4. Analysis of hairy root culture ofRauvolfia serpentina using direct analysis in real time mass spectrometric technique

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