Aaptamine Alkaloids from the Vietnamese Sponge Aaptos sp-Reference-Cited by-同舟云学术

Aaptamine Alkaloids from the Vietnamese Sponge Aaptos sp

Published:2009-08 Issue:8 Volume:4 Page:1934578X0900400
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Shubina Larisa K.¹,Kalinovsky Anatoly I.¹,Fedorov Sergey N.¹,Radchenko Oleg S.¹,Denisenko Vladimir A.¹,Dmitrenok Pavel S.¹,Dyshlovoy Sergey A.¹,Krasokhin Vladimir B.¹,Stonik Valentin A.¹

Affiliation:

1. Laboratory of Chemistry MaNaPro, Pacific Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 690022 Vladivostok, Russia

Abstract

A series of aaptamines, including one new alkaloid (1), were isolated from the marine sponge Aaptos sp. collected in Vietnamese waters. The structure of 1 was elucidated using NMR and HRESIMS, as well as by chemical transformation of 1 to the previously known aaptamine and established as 3-N-morpholinyl-9-demethyl(oxy)aaptamine. The isolated compounds showed a potential cancer preventive activity.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X0900400813

Reference16 articles.

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2. α-Adrenoceptor blocking action of aaptamine, a novel marine natural product, in vascular smooth muscle

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4. Aaptamines. Novel benzo[de][1,6]naphthyridines from the Okinawan marine sponge Aaptos aaptos

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