Lignans from the Stem of Cinnamomum camphora-Reference-Cited by-同舟云学术

Lignans from the Stem of Cinnamomum camphora

Published:2006-01 Issue:1 Volume:1 Page:1934578X0600100
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Hsieh TJ¹,Chen CH²,Lo WL¹,Chen CY¹

Affiliation:

1. Basic Medical Science Education Center, Fooyin University, Kaohsiung County, Taiwan, R.O.C.

2. Department of Medical Technology, Fooyin University, Kaohsiung County, Taiwan, R.O.C.

Abstract

(+)-Diasesamin (1), (+)-sesamin (2), (+)-episesamin, stearic acid, palmitic acid, a mixture of β-sitosterol and stigmasterol, and a mixture of β-sitosterol-D-glucoside and stigmasterol-D-glucoside were isolated from the stems of Cinnamomum camphora (L.) Presl.. Among these compounds, 1 is obtained for the first time from a natural source. The cytotoxicity of 2 on Hep G2 and HeLa cell cancer lines was also investigated. The flow cytometric assay results indicated that 2 elicited a decrease in the percentage of the S phase of the cell cycle in Hep G2 cells after incubation for 24 h. These results reflect that 2 inhibited the DNA synthetic event in Hep G2 cells.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X0600100104

Reference12 articles.

1. 1-(ω-Hydroxyfattyacyl)glycerols and two flavanols fromCinnamomum camphora

2. A novel cyclopentenone, 5-dodecanyl-4-hydroxy-4-methyl-2-cyclopentenone from Cinnamomum camphora

3. Two acyclic monoterpene diols from Cinnamomum camphorha

4. New Lignans and Cytotoxic Constituents fromWikstroemia lanceolata

5. On the Constituents of Seeds of Horsfieldia iryaghedhi WARB. I

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