O-Methylheptaphylline from Clausena suffruticosa-Reference-Cited by-同舟云学术

O-Methylheptaphylline from Clausena suffruticosa

Published:2008-05 Issue:5 Volume:3 Page:1934578X0800300
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Begum Rokeya¹²,Rahman Mohammad S.³,Chowdhury A. M. Sarwaruddin¹,Rahman M. Mukhlesur⁴,Rashid Mohammad A.³

Affiliation:

1. Department of Applied Chemistry and Chemical Technology, University of Dhaka, Dhaka-1000, Bangladesh

2. On leave from the Department of Agricultural Chemistry, Sher-e-Bangla Agricultural University, Dhaka-1207, Bangladesh

3. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh

4. Centre for Pharmacognosy and Phytotherapy, The School of Pharmacy, University of London, 29–39 Brunswick Square, London WC1N 1AX, UK

Abstract

O-Methylheptaphylline (1), together with capnolactone (2), were isolated from Clausena suffruticosa. The structure of 1 was established unambiguously by a series of 1D and 2D-NMR analyses. The cytotoxic activity of 1 and 2 was determined against brine shrimp nauplii and the LC50 values recorded were 0.56 μg/mL and 7.94 μg/mL, respectively.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X0800300526

Reference20 articles.

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2. KirtikarKR, BasuBD, AnICS. (1980) Indian Medicinal Plants. Vol. 1, Bishen Singh Mahendra Pal Singh, India, pp. 475–478.

3. YusufM, ChowdhuryJU, WahabMA, BegumJ. (1994) Medicinal Plants of Bangladesh, BCSIR Laboratories, Chittagong, Bangladesh, p 56.

4. Tryptamine derived amides from Clausena indica

5. Limonoids from Clausena anisata

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