Essential Oil Composition and Antioxidant Capacity of Lippia schomburgkiana

Author:

da Silva Nathalie A.1,da Silva Joyce Kelly R.1,Andrade Eloisa Helena A.2,Carreira Lea Maria M.3,Sousa Pergentino José C.4,Maia José Guilherme S.2

Affiliation:

1. Programa de Pós-Graduação em Química, Universidade Federal do Pará, 66075-900 Belém, PA, Brazil

2. Faculdade de Engenharia Química, Universidade Federal do Pará, Belém, PA, Brazil

3. Coordenação de Botânica, Museu Paraense Emílio Goeldi, 66040-170 Belém, PA, Brazil

4. Faculdade de Farmácia, Universidade Federal do Pará, 66075-900 Belém, PA, Brazil

Abstract

The leaves and fine stems of Lippia schomburgkiana recorded an essential yield of 1.8%, the main constituents of which were 1,8-cineole (64.1%) and α-terpineol (12.0%). The methanol extract of L. schomburgkiana inhibited the DPPH radical, resulting in an EC50 value of 16.1 ± 0.7 μg.mL−1, which is only three times lower than that of trolox (4.7 ± 0.4 μg.mL−1), signifying a high antioxidant activity for the species. The amount of total phenolics (376.7 ± 35.5 mg GAE/g) and the trolox equivalent antioxidant capacity (327.0 ± 24.8 mg TE/g) of the methanol extract confirmed the significant antioxidative capacity of this plant. The brine shrimp bioassay carried out on the oil (49.6 ± 0.4 μg.mL−1) showed high toxicity, providing important evidence of its biological activity. The sensory evaluation of the leaves of L. schomburgkiana showed a percentage acceptance value very close to commercial oregano, indicating that the plant can be used in spice and condiment products.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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