Chemical Composition and Biological Activity of Conyza Bonariensis Essential Oil Collected in Mérida, Venezuela-Reference-Cited by-同舟云学术

Chemical Composition and Biological Activity of Conyza Bonariensis Essential Oil Collected in Mérida, Venezuela

Published:2013-08 Issue:8 Volume:8 Page:1934578X1300800
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Araujo Liliana¹,Moujir Laila M.¹,Rojas Janne²,Rojas Luis²,Carmona Juan³,Rondón María³

Affiliation:

1. Microbiology and Cell Biology Department, University of La Laguna, La Laguna, Tenerife, Spain

2. Research Institute, Faculty of Pharmacy and Bioanalysis, University of Los Andes, Merida, Venezuela

3. Pharmacognosy Department, Faculty of Pharmacy, University of Los Andes, Merida, Venezuela

Abstract

The essential oil from aerial parts of Conyza bonariensis (L) Cronquist collected in Mérida was obtained by hydrodistillation and analysed by GC/MS. The major components were trans-β-farnesene (37.8%), trans-ocimene (20.7%) and β-sesquiphellandrene (9.8%). Cytotoxicity assay was also performed with the essential oil against HeLa (cervix carcinoma), A-459 (lung carcinoma) and MCF-7 (breast adenocarcinoma) human cell lines and against normal Vero cells (African green monkey kidney) with IC50 values ranging from 1.4 to 45.8 μg/mL. Additionally, the essential oil presented a significant bactericidal effect against Bacillus cereus, while a moderate activity was observed against Staphylococcus epidermidis and Candida albicans.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1300800838

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